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Second generation androgen receptor antagonist, TQB3720 abrogates prostate cancer growth via AR/GPX4 axis activated ferroptosis

Purpose: Prostate cancer (PCa) poses a great threat to humans. The study aimed to evaluate the potential of TQB3720 in promoting ferroptosis to suppress prostate cancer, providing a theoretical basis for PCa therapy. Methods: PCa cells and nude mice models were divided into TQB3720, enzalutamide (EN...

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Detalles Bibliográficos
Autores principales:	Zhang, Zhongqing, Xie, Tianlei, Zhang, Shun, Yin, Haoli, Zhang, Xuyu, Zhang, Siyuan, Chen, Wei, Yu, Ding, Qiu, Xuefeng, Zhao, Wei, Guo, Hongqian, Zhuang, Junlong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895946/ https://www.ncbi.nlm.nih.gov/pubmed/36744249 http://dx.doi.org/10.3389/fphar.2023.1110146

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