Integration of metabolomics and transcriptomics provides insights into enhanced osteogenesis in Ano5(Cys360Tyr) knock-in mouse model

INTRODUCTION: Gnathodiaphyseal dysplasia (GDD; OMIM#166260) is a rare autosomal dominant disorder characterized by diaphyseal sclerosis of tubular bones and cemento-osseous lesions in mandibles. GDD is caused by point mutations in the ANO5 gene. However, the mechanisms underlying GDD have not been d...

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Detalles Bibliográficos
Autores principales: Li, Hongyu, Liu, Sirui, Miao, Congcong, Lv, Yan, Hu, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Endocrinology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895949/
https://www.ncbi.nlm.nih.gov/pubmed/36742392
http://dx.doi.org/10.3389/fendo.2023.1117111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895949/
https://www.ncbi.nlm.nih.gov/pubmed/36742392
http://dx.doi.org/10.3389/fendo.2023.1117111

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