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Integration of metabolomics and transcriptomics provides insights into enhanced osteogenesis in Ano5(Cys360Tyr) knock-in mouse model
INTRODUCTION: Gnathodiaphyseal dysplasia (GDD; OMIM#166260) is a rare autosomal dominant disorder characterized by diaphyseal sclerosis of tubular bones and cemento-osseous lesions in mandibles. GDD is caused by point mutations in the ANO5 gene. However, the mechanisms underlying GDD have not been d...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9895949/ https://www.ncbi.nlm.nih.gov/pubmed/36742392 http://dx.doi.org/10.3389/fendo.2023.1117111 |