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Suppression of Tumor or Host Intrinsic CMTM6 Drives Antitumor Cytotoxicity in a PD-L1–Independent Manner

CKLF-like MARVEL transmembrane domain-containing protein 6 (CMTM6) is known to be a regulator of membranal programmed death ligand 1 (PD-L1) stability and a factor associated with malignancy progression, but the effects and mechanisms of CMTM6 on tumor growth, as well as its potential as a target fo...

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Detalles Bibliográficos
Autores principales: Long, Yiru, Chen, Runqiu, Yu, Xiaolu, Tong, Yongliang, Peng, Xionghua, Li, Fanglin, Hu, Chao, Sun, Jianhua, Gong, Likun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896022/
https://www.ncbi.nlm.nih.gov/pubmed/36484740
http://dx.doi.org/10.1158/2326-6066.CIR-22-0439