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A Thermal and Enzymatic Dual‐Stimuli Responsive DNA‐Based Nanomachine for Controlled mRNA Delivery

The extreme instability of mRNA makes the practical application of mRNA‐based vaccines heavily rely on efficient delivery system and cold chain transportation. Herein, a DNA‐based nanomachine, which achieves programmed capture, long‐term storage without cryopreservation, and efficient delivery of mR...

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Detalles Bibliográficos
Autores principales: Li, Feng, Sun, Xiaolei, Yang, Jing, Ren, Jin, Huang, Mengxue, Wang, Shengqi, Yang, Dayong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896069/
https://www.ncbi.nlm.nih.gov/pubmed/36461751
http://dx.doi.org/10.1002/advs.202204905