Personalised azithromycin+metronidazole (PAZAZ), in combination with standard induction therapy, to achieve a faecal microbiome community structure and metagenome changes associated with sustained remission in paediatric Crohn’s disease (CD): protocol of a pilot study

INTRODUCTION: Early relapse in Crohn’s disease (CD) is associated with a more severe disease course. The microbiome plays a crucial role, yet strategies targeting the microbiome are underrepresented in current guidelines. We hypothesise that early manipulation of the microbiome will improve clinical...

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Detalles Bibliográficos
Autores principales: Verburgt, Charlotte M, Dunn, Katherine A, Otley, Anthony, Heyman, Melvin B, Verstraete, Sofia, Sunseri, Withney, Sylvester, Francisco, de Meij, Tim, Comeau, Andre, Langille, Morgan, de Jonge, Wouter J, Benninga, Marc A, Van Limbergen, Johan E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2023
Materias:
Paediatrics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896212/
https://www.ncbi.nlm.nih.gov/pubmed/36725090
http://dx.doi.org/10.1136/bmjopen-2022-064944

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