Non-coding RNAs associated with Prader–Willi syndrome regulate transcription of neurodevelopmental genes in human induced pluripotent stem cells

Mutations and aberrant gene expression during cellular differentiation lead to neurodevelopmental disorders, such as Prader–Willi syndrome (PWS), which results from the deletion of an imprinted locus on paternally inherited chromosome 15. We analyzed chromatin-associated RNA in human induced pluripo...

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Detalles Bibliográficos
Autores principales: Sledziowska, Monika, Winczura, Kinga, Jones, Matt, Almaghrabi, Ruba, Mischo, Hannah, Hebenstreit, Daniel, Garcia, Paloma, Grzechnik, Pawel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896466/
https://www.ncbi.nlm.nih.gov/pubmed/36084040
http://dx.doi.org/10.1093/hmg/ddac228

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