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Exploring the Cocrystal Landscape of Posaconazole by Combining High-Throughput Screening Experimentation with Computational Chemistry

[Image: see text] The development of multicomponent crystal forms, such as cocrystals, represents a means to enhance the dissolution and absorption properties of poorly water-soluble drug compounds. However, the successful discovery of new pharmaceutical cocrystals remains a time- and resource-consu...

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Detalles Bibliográficos
Autores principales: Guidetti, Matteo, Hilfiker, Rolf, Kuentz, Martin, Bauer-Brandl, Annette, Blatter, Fritz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896487/
https://www.ncbi.nlm.nih.gov/pubmed/36747574
http://dx.doi.org/10.1021/acs.cgd.2c01072