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Exploring the Cocrystal Landscape of Posaconazole by Combining High-Throughput Screening Experimentation with Computational Chemistry
[Image: see text] The development of multicomponent crystal forms, such as cocrystals, represents a means to enhance the dissolution and absorption properties of poorly water-soluble drug compounds. However, the successful discovery of new pharmaceutical cocrystals remains a time- and resource-consu...
Autores principales: | Guidetti, Matteo, Hilfiker, Rolf, Kuentz, Martin, Bauer-Brandl, Annette, Blatter, Fritz |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896487/ https://www.ncbi.nlm.nih.gov/pubmed/36747574 http://dx.doi.org/10.1021/acs.cgd.2c01072 |
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