Effects of whole-brain radiation therapy on the blood–brain barrier in immunocompetent and immunocompromised mouse models

BACKGROUND: Approximately 20% of all cancer patients will develop brain metastases in their lifespan. The standard of care for patients with multiple brain metastases is whole-brain radiation therapy, which disrupts the blood–brain barrier. Previous studies have shown inflammatory mediators play a r...

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Detalles Bibliográficos
Autores principales: Blethen, K. E., Sprowls, S. A., Arsiwala, T. A., Wolford, C. P., Panchal, D. M., Fladeland, R. A., Glass, M. J., Dykstra, L. P., Kielkowski, B. N., Blackburn, J. R., Andrick, C. J., Lockman, P. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896731/
https://www.ncbi.nlm.nih.gov/pubmed/36732754
http://dx.doi.org/10.1186/s13014-023-02215-6

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