NRXN1 depletion in the medial prefrontal cortex induces anxiety-like behaviors and abnormal social phenotypes along with impaired neurite outgrowth in rat

BACKGROUND: Neurodevelopmental disorders (NDDs) are a group of disorders induced by abnormal brain developmental processes. The prefrontal cortex (PFC) plays an essential role in executive function, and its role in NDDs has been reported. NDDs are associated with high-risk gene mutations and share p...

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Detalles Bibliográficos
Autores principales: Wu, Di, Zhu, Jiansheng, You, Lianghui, Wang, Jingyu, Zhang, Sufen, Liu, Zhonghui, Xu, Qu, Yuan, Xiaojie, Yang, Lei, Wang, Wei, Tong, Meiling, Hong, Qin, Chi, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896742/
https://www.ncbi.nlm.nih.gov/pubmed/36737720
http://dx.doi.org/10.1186/s11689-022-09471-9

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