Cargando…

Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis

BACKGROUND: Increased acid sphingomyelinase (ASMase) activity is associated with insulin resistance and cardiac dysfunction. However, the effects of ASMase on diabetic cardiomyopathy (DCM) and the molecular mechanism(s) underlying remain to be elucidated. We here investigated whether ASMase caused D...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ruijiao, Duan, Tengfei, Yu, Li, Tang, Yongzhong, Liu, Shikun, Wang, Chunjiang, Fang, Wei-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896821/ https://www.ncbi.nlm.nih.gov/pubmed/36732747 http://dx.doi.org/10.1186/s12933-023-01747-1

Ejemplares similares

NADPH Oxidase-Mediated Activation of Neutral Sphingomyelinase Is Responsible for Diesel Particulate Extract-Induced Keratinocyte Apoptosis
por: Lee, Hyun-Seok, et al.
Publicado: (2020)

Sphingomyelinase promotes oxidant production and skeletal muscle contractile dysfunction through activation of NADPH oxidase
por: Loehr, James A., et al.
Publicado: (2015)

NADPH Oxidase and Neurodegeneration
por: Hernandes, Marina S, et al.
Publicado: (2012)

Apoptosis and signalling in acid sphingomyelinase deficient cells
por: Sillence, Dan J
Publicado: (2001)

NADPH Oxidase Isoforms Are Involved in Glucocorticoid-Induced Preosteoblast Apoptosis
por: Bai, Shu-Cai, et al.
Publicado: (2019)

Analysis of clinical characteristics of mesalazine-induced cardiotoxicity
por: Chen, Junyu, et al.
Publicado: (2022)

Decoding NADPH oxidase 4 expression in human tumors
por: Meitzler, Jennifer L., et al.
Publicado: (2017)

Uric Acid Promotes Apoptosis in Human Proximal Tubule Cells by Oxidative Stress and the Activation of NADPH Oxidase NOX 4
por: Verzola, Daniela, et al.
Publicado: (2014)

Hypertonic Saline Suppresses NADPH Oxidase-Dependent Neutrophil Extracellular Trap Formation and Promotes Apoptosis
por: Nadesalingam, Ajantha, et al.
Publicado: (2018)

NADPH Oxidases and Their Role in Atherosclerosis
por: Poznyak, Anastasia V., et al.
Publicado: (2020)

NADPH Oxidases in Pain Processing
por: Kallenborn-Gerhardt, Wiebke, et al.
Publicado: (2022)

NADPH Oxidases in Aortic Aneurysms
por: Salmon, Morgan
Publicado: (2022)

NADPH oxidase 1 is highly expressed in human large and small bowel cancers
por: Lu, Jiamo, et al.
Publicado: (2020)

NADPH Oxidase: A Potential Target for Treatment of Stroke
por: Zhang, Li, et al.
Publicado: (2016)

Upregulation of NADH/NADPH oxidase 4 by angiotensin II induces podocyte apoptosis
por: Ha, Tae-Sun, et al.
Publicado: (2023)

Oleic, Linoleic and Linolenic Acids Increase ROS Production by Fibroblasts via NADPH Oxidase Activation
por: Hatanaka, Elaine, et al.
Publicado: (2013)

Natural Compounds as Modulators of NADPH Oxidases
por: Maraldi, Tullia
Publicado: (2013)

NADPH Oxidases and Mitochondria in Vascular Senescence
por: Salazar, Gloria
Publicado: (2018)

NADPH oxidases: Current aspects and tools
por: Schröder, Katrin
Publicado: (2020)

Architecture of the NADPH oxidase family of enzymes
por: Ogboo, Blessing C., et al.
Publicado: (2022)

(Poly)phenols and the regulation of NADPH oxidases
por: Fraga, Cesar G., et al.
Publicado: (2023)

NADPH oxidases promote apoptosis by activating ZNRF1 ubiquitin ligase in neurons treated with an exogenously applied oxidant
por: Wakatsuki, Shuji, et al.
Publicado: (2016)

Acid Sphingomyelinase Mediates Oxidized-LDL Induced Apoptosis in Macrophage via Endoplasmic Reticulum Stress
por: Zhao, Min, et al.
Publicado: (2016)

Sodium activates human monocytes via the NADPH oxidase and isolevuglandin formation
por: Ruggeri Barbaro, Natalia, et al.
Publicado: (2020)

Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase‐induced cardiomyopathy: involvement of mitofusin‐2
por: McLaughlin, Declan, et al.
Publicado: (2017)

Holotoxin A(1) Induces Apoptosis by Activating Acid Sphingomyelinase and Neutral Sphingomyelinase in K562 and Human Primary Leukemia Cells
por: Yun, Seong-Hoon, et al.
Publicado: (2018)

Xanthohumol Induces ROS through NADPH Oxidase, Causes Cell Cycle Arrest and Apoptosis
por: Wang, Chun-Ming, et al.
Publicado: (2021)

Serum Level of Xanthine Oxidase, Uric Acid, and NADPH Oxidase 1 in Stage I of Multiple Myeloma
por: Kohsari, Maryam, et al.
Publicado: (2020)

NADPH Oxidase 1 and NADPH Oxidase 4 Have Opposite Prognostic Effects for Patients with Hepatocellular Carcinoma after Hepatectomy
por: Ha, Sang Yun, et al.
Publicado: (2016)

Oscillatory shear stress promotes vein graft intimal hyperplasia via NADPH oxidase-related pathways
por: Yao, Guoqing, et al.
Publicado: (2023)

Boswellic acid inhibits expression of acid sphingomyelinase in intestinal cells
por: Zhang, Yao, et al.
Publicado: (2009)

miR‐322 treatment rescues cell apoptosis and neural tube defect formation through silencing NADPH oxidase 4
por: Liu, Yu‐si, et al.
Publicado: (2020)

Structure of human phagocyte NADPH oxidase in the resting state
por: Liu, Rui, et al.
Publicado: (2022)

Lutein Induces Reactive Oxygen Species-Mediated Apoptosis in Gastric Cancer AGS Cells via NADPH Oxidase Activation
por: Eom, Ju Won, et al.
Publicado: (2023)

The NADPH Oxidase Nox4 and Aging in the Heart
por: Ago, Tetsuro, et al.
Publicado: (2010)

NADPH Oxidase and the Cardiovascular Toxicity Associated with Smoking
por: Kim, Mikyung, et al.
Publicado: (2014)

A Role for NADPH Oxidase in Antigen Presentation
por: Gardiner, Gail J., et al.
Publicado: (2013)

NADPH oxidase in brain injury and neurodegenerative disorders
por: Ma, Merry W., et al.
Publicado: (2017)

Exploiting algal NADPH oxidase for biophotovoltaic energy
por: Anderson, Alexander, et al.
Publicado: (2015)

NADPH Oxidase Deficiency: A Multisystem Approach
por: Giardino, Giuliana, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_htivq3lu31fj6o55tt7lp0rtah