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Acid sphingomyelinase promotes diabetic cardiomyopathy via NADPH oxidase 4 mediated apoptosis

BACKGROUND: Increased acid sphingomyelinase (ASMase) activity is associated with insulin resistance and cardiac dysfunction. However, the effects of ASMase on diabetic cardiomyopathy (DCM) and the molecular mechanism(s) underlying remain to be elucidated. We here investigated whether ASMase caused D...

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Detalles Bibliográficos
Autores principales:	Liu, Ruijiao, Duan, Tengfei, Yu, Li, Tang, Yongzhong, Liu, Shikun, Wang, Chunjiang, Fang, Wei-Jin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896821/ https://www.ncbi.nlm.nih.gov/pubmed/36732747 http://dx.doi.org/10.1186/s12933-023-01747-1

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