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Nucleolin mediates SARS-CoV-2 replication and viral-induced apoptosis of host cells

Host-oriented antiviral therapeutics are promising treatment options to combat COVID-19 and its emerging variants. However, relatively little is known about the cellular proteins hijacked by SARS-CoV-2 for its replication. Here we show that SARS-CoV-2 induces expression and cytoplasmic translocation...

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Detalles Bibliográficos
Autores principales: Merino, Vanessa F., Yan, Yu, Ordonez, Alvaro A., Bullen, C. Korin, Lee, Albert, Saeki, Harumi, Ray, Krishanu, Huang, Tao, Jain, Sanjay K., Pomper, Martin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896859/
https://www.ncbi.nlm.nih.gov/pubmed/36740097
http://dx.doi.org/10.1016/j.antiviral.2023.105550