Cargando…

Nucleolin mediates SARS-CoV-2 replication and viral-induced apoptosis of host cells

Host-oriented antiviral therapeutics are promising treatment options to combat COVID-19 and its emerging variants. However, relatively little is known about the cellular proteins hijacked by SARS-CoV-2 for its replication. Here we show that SARS-CoV-2 induces expression and cytoplasmic translocation...

Descripción completa

Detalles Bibliográficos
Autores principales:	Merino, Vanessa F., Yan, Yu, Ordonez, Alvaro A., Bullen, C. Korin, Lee, Albert, Saeki, Harumi, Ray, Krishanu, Huang, Tao, Jain, Sanjay K., Pomper, Martin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896859/ https://www.ncbi.nlm.nih.gov/pubmed/36740097 http://dx.doi.org/10.1016/j.antiviral.2023.105550

Ejemplares similares

Host Cell Nucleolin Is Required To Maintain the Architecture of Human Cytomegalovirus Replication Compartments
por: Strang, Blair L., et al.
Publicado: (2012)

Interaction of Nucleolin with the Fusion Protein of Avian Metapneumovirus Subgroup C Contributes to Viral Replication
por: Wang, Dedong, et al.
Publicado: (2022)

Binding of cellular nucleolin with the viral core RNA G-quadruplex structure suppresses HCV replication
por: Bian, Wen-Xiu, et al.
Publicado: (2019)

Nucleolin interacts with influenza A nucleoprotein and contributes to viral ribonucleoprotein complexes nuclear trafficking and efficient influenza viral replication
por: Terrier, Olivier, et al.
Publicado: (2016)

Seneca Valley Virus 3C(pro) Mediates Cleavage and Redistribution of Nucleolin To Facilitate Viral Replication
por: Song, Jiangwei, et al.
Publicado: (2022)

Nucleolar protein nucleolin functions in replication stress–induced DNA damage responses
por: Kawamura, Kasumi, et al.
Publicado: (2019)

Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression
por: Kumar, Deepshikha, et al.
Publicado: (2016)

Targeting Host Cell Surface Nucleolin for RSV Therapy: Challenges and Opportunities
por: Mastrangelo, Peter, et al.
Publicado: (2017)

Involvement of VCP/UFD1/Nucleolin in the viral entry of Enterovirus A species
por: Yan, Jingjing, et al.
Publicado: (2020)

Sulforaphane exhibits antiviral activity against pandemic SARS-CoV-2 and seasonal HCoV-OC43 coronaviruses in vitro and in mice
por: Ordonez, Alvaro A., et al.
Publicado: (2022)

Formation of a Complex between Nucleolin and Replication Protein a after Cell Stress Prevents Initiation of DNA Replication
por: Daniely, Yaron, et al.
Publicado: (2000)

AS1411 Nucleolin-Specific Binding Aptamers Reduce Pathological Angiogenesis through Inhibition of Nucleolin Phosphorylation
por: Iturriaga-Goyon, Emilio, et al.
Publicado: (2021)

SET mediates TCE-induced liver cell apoptosis through dephosphorylation and upregulation of nucleolin
por: Ren, Xiaohu, et al.
Publicado: (2017)

Expression of Nucleolin Affects Microtubule Dynamics
por: Gaume, Xavier, et al.
Publicado: (2016)

hnRNPL and nucleolin bind LINE-1 RNA and function as host factors to modulate retrotransposition
por: Peddigari, Suresh, et al.
Publicado: (2013)

Cell surface nucleolin is a novel ADAMTS5 receptor mediating endothelial cell apoptosis
por: Kirman, Dogan Can, et al.
Publicado: (2022)

Host Phylogeny Determines Viral Persistence and Replication in Novel Hosts
por: Longdon, Ben, et al.
Publicado: (2011)

Host Factors Promoting Viral RNA Replication
por: Nagy, Peter D., et al.
Publicado: (2008)

Nucleolin stabilizes G-quadruplex structures folded by the LTR promoter and silences HIV-1 viral transcription
por: Tosoni, Elena, et al.
Publicado: (2015)

Cancer Stem Cells and Nucleolin as Drivers of Carcinogenesis
por: Carvalho, Laura Sofia, et al.
Publicado: (2021)

Overexpression of Nucleolin and Associated Genes in Prostate Cancer
por: Firlej, Virginie, et al.
Publicado: (2022)

Insights into the binding mode of AS1411 aptamer to nucleolin
por: Bie, Lihua, et al.
Publicado: (2022)

Anti-nucleolin aptamer AS1411: an advancing therapeutic
por: Van den Avont, Alexander, et al.
Publicado: (2023)

Inferring Host Gene Subnetworks Involved in Viral Replication
por: Chasman, Deborah, et al.
Publicado: (2014)

Determination of Host RNA Helicases Activity in Viral Replication
por: Sharma, Amit, et al.
Publicado: (2012)

In vivo Study of the Histone Chaperone Activity of Nucleolin by FRAP
por: Gaume, Xavier, et al.
Publicado: (2011)

Roles of nucleolin: Focus on cancer and anti-cancer therapy
por: Chen, Zhuo, et al.
Publicado: (2016)

A novel nucleolin-binding peptide for Cancer Theranostics
por: Kim, Jae-Hyun, et al.
Publicado: (2020)

A novel role for nucleolin in splice site selection
por: Shefer, Kinneret, et al.
Publicado: (2022)

Nucleolin: a cell portal for viruses, bacteria, and toxins
por: Tonello, Fiorella, et al.
Publicado: (2022)

Nucleolin expression has prognostic value in neuroblastoma patients
por: Cangelosi, Davide, et al.
Publicado: (2022)

Nucleolin Therapeutic Targeting Decreases Pancreatic Cancer Immunosuppression
por: Ponzo, Matteo, et al.
Publicado: (2022)

Avian Leucosis Virus-Host Interaction: The Involvement of Host Factors in Viral Replication
por: Tang, Shuang, et al.
Publicado: (2022)

The host phylogeny determines viral infectivity and replication across Staphylococcus host species
por: Walsh, Sarah K., et al.
Publicado: (2023)

The roles of lipids in SARS-CoV-2 viral replication and the host immune response
por: Theken, Katherine N., et al.
Publicado: (2021)

Nucleolin Down-Regulation Is Involved in ADP-Induced Cell Cycle Arrest in S Phase and Cell Apoptosis in Vascular Endothelial Cells
por: Wang, Wenmeng, et al.
Publicado: (2014)

The dependence of viral RNA replication on co-opted host factors
por: Nagy, Peter D., et al.
Publicado: (2011)

Viral and host determinants of RNA virus vector replication and expression
por: Ahlquist, Paul, et al.
Publicado: (2005)

Ribonucleoprotein Particles Containing Non-Coding Y RNAs, Ro60, La and Nucleolin Are Not Required for Y RNA Function in DNA Replication
por: Langley, Alexander R., et al.
Publicado: (2010)

Dynamic single-cell RNA sequencing reveals BCG vaccination curtails SARS-CoV-2 induced disease severity and lung inflammation
por: Singh, Alok K., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_9agk0csc95l8qn65d1cr0pj8n0