Cytoplasmic p53 aggregates accumulated in p53-mutated cancer correlate with poor prognosis

Recent studies suggested that aggregates of mutant p53 proteins may propagate and impair normal p53 functioning in recipient cells. Our previous study showed that cancer cell-derived p53 aggregates that cells internalized interfered with p53-dependent apoptosis in recipient cells. However, involveme...

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Detalles Bibliográficos
Autores principales: Iwahashi, Naoyuki, Ikezaki, Midori, Komohara, Yoshihiro, Fujiwara, Yukio, Noguchi, Tomoko, Nishioka, Kaho, Sakai, Kazuko, Nishio, Kazuto, Ueda, Mitsuharu, Ihara, Yoshito, Uchimura, Kenji, Ino, Kazuhiko, Nishitsuji, Kazuchika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Biological, Health, and Medical Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896898/
https://www.ncbi.nlm.nih.gov/pubmed/36741442
http://dx.doi.org/10.1093/pnasnexus/pgac128

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