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N-linked glycosylation enhances hemagglutinin stability in avian H5N6 influenza virus to promote adaptation in mammals

Clade 2.3.4.4 avian H5Ny viruses, namely H5N2, H5N6, and H5N8, have exhibited unprecedented intercontinental spread in poultry. Among them, only H5N6 viruses are frequently reported to infect mammals and cause serious human infections. In this study, the genetic and biological characteristics of sur...

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Detalles Bibliográficos
Autores principales: Sun, Honglei, Deng, Guojing, Sun, Haoran, Song, Jingwei, Zhang, Wei, Li, Han, Wei, Xiaohui, Li, Fangtao, Zhang, Xin, Liu, Jiyu, Pu, Juan, Sun, Yipeng, Tong, Qi, Bi, Yuhai, Xie, Yufeng, Qi, Jianxun, Chang, Kin-Chow, Gao, George Fu, Liu, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896958/
https://www.ncbi.nlm.nih.gov/pubmed/36741455
http://dx.doi.org/10.1093/pnasnexus/pgac085

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