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Rapamycin relieves lupus nephritis by regulating TIM-3 and CD4(+)CD25(+)Foxp3(+) Treg cells in an MRL/lpr mouse model

Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus (SLE) and is an important driver of morbidity and mortality in SLE. Treg cells and TIM-3 play an important role in the pathogenesis of LN. The beneficial effect of rapamycin on LN has been confirmed in both mouse models and...

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Detalles Bibliográficos
Autores principales:	Gao, Yan-fang, Fan, Xiu-zhao, Li, Rong-shan, Zhou, Xiao-shuang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Termedia Publishing House 2022
Materias:	Experimental Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9896989/ https://www.ncbi.nlm.nih.gov/pubmed/36817267 http://dx.doi.org/10.5114/ceji.2022.118778

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