Safety, tolerability, and pharmacokinetics of single and multiple ascending Oral doses of DA‐8010 in healthy subjects: First‐in‐human phase I study

This study assessed the safety, tolerability, and pharmacokinetics of single and multiple oral doses of DA‐8010, a muscarinic M(3) receptor antagonist, in healthy subjects. This was a randomized, double‐blind, placebo‐controlled, ascending single (Part A: 1, 2.5, 5, 20, and 40 mg QD fasted and 10 mg...

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Detalles Bibliográficos
Autores principales: Lee, Dae Young, Lee, Min Jung, Ryu, Chaelim, Lee, Heewon, Brooks, Ashley
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897050/
https://www.ncbi.nlm.nih.gov/pubmed/36734627
http://dx.doi.org/10.1002/prp2.1040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897050/
https://www.ncbi.nlm.nih.gov/pubmed/36734627
http://dx.doi.org/10.1002/prp2.1040

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