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Safety, tolerability, and pharmacokinetics of single and multiple ascending Oral doses of DA‐8010 in healthy subjects: First‐in‐human phase I study
This study assessed the safety, tolerability, and pharmacokinetics of single and multiple oral doses of DA‐8010, a muscarinic M(3) receptor antagonist, in healthy subjects. This was a randomized, double‐blind, placebo‐controlled, ascending single (Part A: 1, 2.5, 5, 20, and 40 mg QD fasted and 10 mg...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897050/ https://www.ncbi.nlm.nih.gov/pubmed/36734627 http://dx.doi.org/10.1002/prp2.1040 |