Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview

Olfactory disorders may be temporary or permanent and can have various causes. Currently, many COVID-19 patients report a reduced or complete loss of olfactory function. A wide range of treatment options have been investigated in the past, such as olfactory training, acupuncture, medical therapy, tr...

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Autores principales: Gunder, N., Dörig, P., Witt, M., Welge-Lüssen, A., Menzel, S., Hummel, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Medizin 2023
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897160/
https://www.ncbi.nlm.nih.gov/pubmed/36734997
http://dx.doi.org/10.1007/s00106-022-01249-8
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author Gunder, N.
Dörig, P.
Witt, M.
Welge-Lüssen, A.
Menzel, S.
Hummel, T.
author_facet Gunder, N.
Dörig, P.
Witt, M.
Welge-Lüssen, A.
Menzel, S.
Hummel, T.
author_sort Gunder, N.
collection PubMed
description Olfactory disorders may be temporary or permanent and can have various causes. Currently, many COVID-19 patients report a reduced or complete loss of olfactory function. A wide range of treatment options have been investigated in the past, such as olfactory training, acupuncture, medical therapy, transcranial magnetic stimulation, or surgical excision of olfactory epithelium, e.g., in severe qualitative smell disorders. The development of a bioelectric nose, e.g., in connection with direct electrical stimulation or transplantation of olfactory epithelium or stem cells, represent treatment options of the future. The basis of these developments and the state of knowledge is discussed in the following work.
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spelling pubmed-98971602023-02-06 Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview Gunder, N. Dörig, P. Witt, M. Welge-Lüssen, A. Menzel, S. Hummel, T. HNO Review Articles Olfactory disorders may be temporary or permanent and can have various causes. Currently, many COVID-19 patients report a reduced or complete loss of olfactory function. A wide range of treatment options have been investigated in the past, such as olfactory training, acupuncture, medical therapy, transcranial magnetic stimulation, or surgical excision of olfactory epithelium, e.g., in severe qualitative smell disorders. The development of a bioelectric nose, e.g., in connection with direct electrical stimulation or transplantation of olfactory epithelium or stem cells, represent treatment options of the future. The basis of these developments and the state of knowledge is discussed in the following work. Springer Medizin 2023-02-03 2023 /pmc/articles/PMC9897160/ /pubmed/36734997 http://dx.doi.org/10.1007/s00106-022-01249-8 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Review Articles
Gunder, N.
Dörig, P.
Witt, M.
Welge-Lüssen, A.
Menzel, S.
Hummel, T.
Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title_full Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title_fullStr Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title_full_unstemmed Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title_short Future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
title_sort future therapeutic strategies for olfactory disorders: electrical stimulation, stem cell therapy, and transplantation of olfactory epithelium—an overview
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897160/
https://www.ncbi.nlm.nih.gov/pubmed/36734997
http://dx.doi.org/10.1007/s00106-022-01249-8
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