Cargando…

Nucleic DHX9 cooperates with STAT1 to transcribe interferon-stimulated genes

RNA helicase DHX9 has been extensively characterized as a transcriptional regulator, which is consistent with its mostly nucleic localization. It is also involved in recognizing RNA viruses in the cytoplasm. However, there is no in vivo data to support the antiviral role of DHX9; meanwhile, as a nuc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Xingxing, Wang, Decai, Zhang, Guorong, Zhou, Tingyue, Wei, Zheng, Yang, Yi, Zheng, Yunjiang, Lei, Xuqiu, Tao, Wanyin, Wang, Anmin, Li, Mingsong, Flavell, Richard A., Zhu, Shu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897671/ https://www.ncbi.nlm.nih.gov/pubmed/36735791 http://dx.doi.org/10.1126/sciadv.add5005

Ejemplares similares

Structural basis of the transcription termination factor Rho engagement with transcribing RNA polymerase from Thermus thermophilus
por: Murayama, Yuko, et al.
Publicado: (2023)

XPF interacts with TOP2B for R-loop processing and DNA looping on actively transcribed genes
por: Chatzinikolaou, Georgia, et al.
Publicado: (2023)

Zika virus noncoding RNA cooperates with the viral protein NS5 to inhibit STAT1 phosphorylation and facilitate viral pathogenesis
por: Slonchak, Andrii, et al.
Publicado: (2022)

Two interacting transcriptional coactivators cooperatively control plant immune responses
por: Chen, Huan, et al.
Publicado: (2021)

LATS1 is a central signal transmitter for achieving full type-I interferon activity
por: Zuo, Yibo, et al.
Publicado: (2022)

Interferon b drives intestinal regeneration after radiation
por: Leibowitz, Brian J., et al.
Publicado: (2021)

STAT1 maintains naïve CD8(+) T cell quiescence by suppressing the type I IFN-STAT4-mTORC1 signaling axis
por: Kye, Yoon-Chul, et al.
Publicado: (2021)

Insertional activation of STAT3 and LCK by HIV-1 proviruses in T cell lymphomas
por: Mellors, John W., et al.
Publicado: (2021)

Spatiotemporal gating of Stat nuclear influx by Drosophila Npas4 in collective cell migration
por: Wu, Jhen-Wei, et al.
Publicado: (2022)

MALAT1 modulates alternative splicing by cooperating with the splicing factors PTBP1 and PSF
por: Miao, Hui, et al.
Publicado: (2022)

FIRRM cooperates with FIGNL1 to promote RAD51 disassembly during DNA repair
por: Pinedo-Carpio, Edgar, et al.
Publicado: (2023)

H3K9 dimethylation safeguards cancer cells against activation of the interferon pathway
por: Hansen, Anne Meldgaard, et al.
Publicado: (2022)

Transcription and splicing regulation by NLRC5 shape the interferon response in human pancreatic β cells
por: Szymczak, Florian, et al.
Publicado: (2022)

HSF2 cooperates with HSF1 to drive a transcriptional program critical for the malignant state
por: Smith, Roger S., et al.
Publicado: (2022)

The immune checkpoint B7-H3 (CD276) regulates adipocyte progenitor metabolism and obesity development
por: Picarda, Elodie, et al.
Publicado: (2022)

Two cooperative binding sites sensitize PI(4,5)P(2) recognition by the tubby domain
por: Thallmair, Veronika, et al.
Publicado: (2022)

ATP-competitive inhibitors modulate the substrate binding cooperativity of a kinase by altering its conformational entropy
por: Olivieri, Cristina, et al.
Publicado: (2022)

Cooperation between physiological defenses and immune resistance produces asymptomatic carriage of a lethal bacterial pathogen
por: Chen, Grischa Y., et al.
Publicado: (2023)

A cooperative network at the nuclear envelope counteracts LINC-mediated forces during oogenesis in C. elegans
por: Liu, Chenshu, et al.
Publicado: (2023)

Therapeutic KRAS(G12C) inhibition drives effective interferon-mediated antitumor immunity in immunogenic lung cancers
por: Mugarza, Edurne, et al.
Publicado: (2022)

Screening of ETO2-GLIS2–induced Super Enhancers identifies targetable cooperative dependencies in acute megakaryoblastic leukemia
por: Benbarche, Salima, et al.
Publicado: (2022)

ETV4 mediates dosage-dependent prostate tumor initiation and cooperates with p53 loss to generate prostate cancer
por: Li, Dan, et al.
Publicado: (2023)

Exosome-mediated genetic reprogramming of tumor-associated macrophages by exoASO-STAT6 leads to potent monotherapy antitumor activity
por: Kamerkar, Sushrut, et al.
Publicado: (2022)

An IL-6/STAT3/MR/FGF21 axis mediates heart-liver cross-talk after myocardial infarction
por: Sun, Jian-Yong, et al.
Publicado: (2023)

Cooperative assembly of a designer peptide and silk fibroin into hybrid nanofiber gels for neural regeneration after spinal cord injury
por: Feng, Feng, et al.
Publicado: (2023)

Na, K-ATPase α1 cooperates with its endogenous ligand to reprogram immune microenvironment of lung carcinoma and promotes immune escape
por: Yang, Kaiyong, et al.
Publicado: (2023)

A highly selective JAK3 inhibitor is developed for treating rheumatoid arthritis by suppressing γc cytokine–related JAK-STAT signal
por: Chen, Chengjuan, et al.
Publicado: (2022)

The Hippo pathway mediates Semaphorin signaling
por: Meng, Zhipeng, et al.
Publicado: (2022)

m(6)A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB–mediated antiapoptotic pathway
por: Zhang, Ting, et al.
Publicado: (2022)

PRP4KA phosphorylates SERRATE for degradation via 20S proteasome to fine-tune miRNA production in Arabidopsis
por: Wang, Lin, et al.
Publicado: (2022)

Global biogeography and projection of soil antibiotic resistance genes
por: Zheng, Dongsheng, et al.
Publicado: (2022)

TIPE2 is a checkpoint of natural killer cell maturation and antitumor immunity
por: Bi, Jiacheng, et al.
Publicado: (2021)

Epigenetic controls of Sonic hedgehog guarantee fidelity of epithelial adult stem cells trajectory in regeneration
por: Yu, Fanyuan, et al.
Publicado: (2022)

The molecular mechanism of sialic acid transport mediated by Sialin
por: Hu, Wenxin, et al.
Publicado: (2023)

Structural basis for the ubiquitination of G protein βγ subunits by KCTD5/Cullin3 E3 ligase
por: Jiang, Wentong, et al.
Publicado: (2023)

Inhibition of fungal pathogenicity by targeting the H(2)S-synthesizing enzyme cystathionine β-synthase
por: Chang, Wenqiang, et al.
Publicado: (2022)

Lnc956 regulates mouse embryonic stem cell differentiation in response to DNA damage in a p53-independent pathway
por: Ma, Huaixiao, et al.
Publicado: (2023)

Twin-bioengine self-adaptive micro/nanorobots using enzyme actuation and macrophage relay for gastrointestinal inflammation therapy
por: Zhang, Baozhen, et al.
Publicado: (2023)

Injectable, self-healing hydrogel adhesives with firm tissue adhesion and on-demand biodegradation for sutureless wound closure
por: Ren, Hui, et al.
Publicado: (2023)

Pathogen effector AvrSr35 triggers Sr35 resistosome assembly via a direct recognition mechanism
por: Zhao, Yan-Bo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_osua3u7tecb9pcp1i0q2tkal76