Cargando…

Inhibition of EZH2 mitigates peritoneal fibrosis and lipid precipitation in peritoneal mesothelial cells mediated by klotho

BACKGROUND: Peritoneal fibrosis caused by long-term peritoneal dialysis (PD) is the main reason why patients withdraw from PD treatment. Lipid accumulation in the peritoneum was shown to participate in fibrosis, and klotho is a molecule involved in lipid metabolism. GSK343 (enhancer of zeste 2 polyc...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Qinglian, Sun, Jingshu, Wang, Rong, Sun, Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2023
Materias:	Clinical Study
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897791/ https://www.ncbi.nlm.nih.gov/pubmed/36724065 http://dx.doi.org/10.1080/0886022X.2022.2149411

Ejemplares similares

Mechanisms of Peritoneal Mesothelial Cells in Peritoneal Adhesion
por: Wang, Ruipeng, et al.
Publicado: (2022)

Expression of XBP1s in peritoneal mesothelial cells is critical for inflammation-induced peritoneal fibrosis
por: Liu, An, et al.
Publicado: (2019)

Trehalose ameliorates peritoneal fibrosis by promoting Snail degradation and inhibiting mesothelial-to-mesenchymal transition in mesothelial cells
por: Miyake, Taito, et al.
Publicado: (2020)

Nintedanib attenuates peritoneal fibrosis by inhibiting mesothelial‐to‐mesenchymal transition, inflammation and angiogenesis
por: Liu, Feng, et al.
Publicado: (2021)

Histone deacetylase 6 inhibition counteracts the epithelial–mesenchymal transition of peritoneal mesothelial cells and prevents peritoneal fibrosis
por: Xu, Liuqing, et al.
Publicado: (2017)

RhoA/Rho-kinase triggers epithelial-mesenchymal transition in mesothelial cells and contributes to the pathogenesis of dialysis-related peritoneal fibrosis
por: Wang, Qinglian, et al.
Publicado: (2018)

Adrenomedullin in peritoneal effluent expressed by peritoneal mesothelial cells
por: Kono, Rika, et al.
Publicado: (2013)

Role of Peritoneal Mesothelial Cells in the Progression of Peritoneal Metastases
por: Li, Junliang, et al.
Publicado: (2022)

Metformin ameliorates the Phenotype Transition of Peritoneal Mesothelial Cells and Peritoneal Fibrosis via a modulation of Oxidative Stress
por: Shin, Hyun-Soo, et al.
Publicado: (2017)

Fibrosis of mesothelial cell-induced peritoneal implantation of ovarian cancer cells
por: Wang, Jinou, et al.
Publicado: (2018)

Angiotensin II type 2 receptor prevents extracellular matrix accumulation in human peritoneal mesothelial cell by ameliorating lipid disorder via LOX‐1 suppression
por: Liu, Jing, et al.
Publicado: (2022)

The role of human peritoneal mesothelial cells in the fibrosis and progression of gastric cancer
por: TSUKADA, TOMOYA, et al.
Publicado: (2012)

MiR-29b may suppresses peritoneal metastases through inhibition of the mesothelial–mesenchymal transition (MMT) of human peritoneal mesothelial cells
por: Kimura, Yuki, et al.
Publicado: (2022)

Fibrin-Induced Epithelial-to-Mesenchymal Transition of Peritoneal Mesothelial Cells as a Mechanism of Peritoneal Fibrosis: Effects of Pentoxifylline
por: Fang, Cheng-Chung, et al.
Publicado: (2012)

TGF-β1 induces peritoneal fibrosis by activating the Smad2 pathway in mesothelial cells and promotes peritoneal carcinomatosis
por: Lv, Zhi-Dong, et al.
Publicado: (2023)

Importance of human peritoneal mesothelial cells in the progression, fibrosis, and control of gastric cancer: inhibition of growth and fibrosis by tranilast
por: Saito, Hiroto, et al.
Publicado: (2017)

Extracellular vesicle‐packaged ILK from mesothelial cells promotes fibroblast activation in peritoneal fibrosis
por: Huang, Qiang, et al.
Publicado: (2023)

Mechanisms of Epithelial-Mesenchymal Transition of Peritoneal Mesothelial Cells During Peritoneal Dialysis
por: Lee, Hi Bahl, et al.
Publicado: (2007)

Matrine suppresses lipopolysaccharide-induced fibrosis in human peritoneal mesothelial cells by inhibiting the epithelial-mesenchymal transition
por: Li, Yi-Zheng, et al.
Publicado: (2019)

Hydrogen sulfide inhibits epithelial-mesenchymal transition in peritoneal mesothelial cells
por: Cheng, Shengnan, et al.
Publicado: (2018)

The influence of seasonal factors on the incidence of peritoneal dialysis-associated peritonitis
por: Zeng, Ying, et al.
Publicado: (2020)

PPARγ alleviates peritoneal fibrosis progression along with promoting GLUT1 expression and suppressing peritoneal mesothelial cell proliferation
por: Feng, Junxia, et al.
Publicado: (2022)

SPHK1‐induced autophagy in peritoneal mesothelial cell enhances gastric cancer peritoneal dissemination
por: Yin, Songcheng, et al.
Publicado: (2019)

Pathophysiological Changes to the Peritoneal Membrane during PD-Related Peritonitis: The Role of Mesothelial Cells
por: Yung, Susan, et al.
Publicado: (2012)

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis
por: Loureiro, Jesús, et al.
Publicado: (2013)

Loosening of the mesothelial barrier as an early therapeutic target to preserve peritoneal function in peritoneal dialysis
por: Kang, Duk-Hee
Publicado: (2020)

Red blood cell distribution width and peritoneal dialysis-associated peritonitis prognosis
por: He, Peng, et al.
Publicado: (2020)

The Effect of Statin on Epithelial-Mesenchymal Transition in Peritoneal Mesothelial Cells
por: Chang, Tae Ik, et al.
Publicado: (2014)

The Mesothelial Origin of Carcinoma Associated-Fibroblasts in Peritoneal Metastasis
por: Rynne-Vidal, Angela, et al.
Publicado: (2015)

Serum Sphingosine-1-phosphate level and peritonitis in peritoneal dialysis patients
por: Bai, Qiong, et al.
Publicado: (2020)

Technique failure in peritoneal dialysis-related peritonitis: risk factors and patient survival
por: Yu, Jin, et al.
Publicado: (2023)

Effects of prophylactic antibiotics before peritoneal dialysis catheter implantation on the clinical outcomes of peritoneal dialysis patients
por: Liu, Xihui, et al.
Publicado: (2019)

Are the Mesothelial-to-Mesenchymal Transition, Sclerotic Peritonitis Syndromes, and Encapsulating Peritoneal Sclerosis Part of the Same Process?
por: Loureiro, Jesús, et al.
Publicado: (2013)

Risk factors of severe peritoneal sclerosis in chronic peritoneal dialysis patients
por: Alatab, Sudabeh, et al.
Publicado: (2016)

The effect of rural and urban life on peritonitis rates in chronic peritoneal patients
por: Çankaya, Erdem, et al.
Publicado: (2023)

Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells
por: Kang, Seok Hui, et al.
Publicado: (2019)

Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer
por: Pascual-Antón, Lucía, et al.
Publicado: (2021)

Activation of salt-inducible kinase 2 promotes the viability of peritoneal mesothelial cells exposed to stress of peritoneal dialysis
por: Wang, H-H, et al.
Publicado: (2016)

Elevated triglyceride-glucose index predisposes to the initial episode of peritonitis in chronic peritoneal dialysis patients
por: Liu, Guiling, et al.
Publicado: (2023)

Activating SIRT3 in peritoneal mesothelial cells alleviates postsurgical peritoneal adhesion formation by decreasing oxidative stress and inhibiting the NLRP3 inflammasome
por: Shen, Tianli, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_ksbmqjei2a6ch69cfnniiiehfb