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Biochemical analysis of SARS-CoV-2 Nsp13 helicase implicated in COVID-19 and factors that regulate its catalytic functions

Replication of the 30-kilobase genome of SARS-CoV-2, responsible for COVID-19, is a key step in the coronavirus life cycle that requires a set of virally encoded nonstructural proteins such as the highly conserved Nsp13 helicase. However, the features that contribute to catalytic properties of Nsp13...

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Detalles Bibliográficos
Autores principales:	Sommers, Joshua A., Loftus, Lorin N., Jones, Martin P., Lee, Rebecca A., Haren, Caitlin E., Dumm, Adaira J., Brosh, Robert M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9897874/ https://www.ncbi.nlm.nih.gov/pubmed/36739951 http://dx.doi.org/10.1016/j.jbc.2023.102980

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