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Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys
BACKGROUND: Patients with coronary heart disease (CHD) with and without diabetes mellitus have an increased risk of recurrent events requiring multifactorial secondary prevention of cardiovascular risk factors. We compared prevalences of cardiovascular risk factors and its determinants including lif...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898414/ https://www.ncbi.nlm.nih.gov/pubmed/36166067 http://dx.doi.org/10.1007/s00392-022-02093-0 |
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author | Ungethüm, K. Wiedmann, S. Wagner, M. Leyh, R. Ertl, G. Frantz, S. Geisler, T. Karmann, W. Prondzinsky, R. Herdeg, C. Noutsias, M. Ludwig, T. Käs, J. Klocke, B. Krapp, J. Wood, D. Kotseva, K. Störk, S. Heuschmann, P. U. |
author_facet | Ungethüm, K. Wiedmann, S. Wagner, M. Leyh, R. Ertl, G. Frantz, S. Geisler, T. Karmann, W. Prondzinsky, R. Herdeg, C. Noutsias, M. Ludwig, T. Käs, J. Klocke, B. Krapp, J. Wood, D. Kotseva, K. Störk, S. Heuschmann, P. U. |
author_sort | Ungethüm, K. |
collection | PubMed |
description | BACKGROUND: Patients with coronary heart disease (CHD) with and without diabetes mellitus have an increased risk of recurrent events requiring multifactorial secondary prevention of cardiovascular risk factors. We compared prevalences of cardiovascular risk factors and its determinants including lifestyle, pharmacotherapy and diabetes mellitus among patients with chronic CHD examined within the fourth and fifth EUROASPIRE surveys (EA-IV, 2012–13; and EA-V, 2016–17) in Germany. METHODS: The EA initiative iteratively conducts European-wide multicenter surveys investigating the quality of secondary prevention in chronic CHD patients aged 18 to 79 years. The data collection in Germany was performed during a comprehensive baseline visit at study centers in Würzburg (EA-IV, EA-V), Halle (EA-V), and Tübingen (EA-V). RESULTS: 384 EA-V participants (median age 69.0 years, 81.3% male) and 536 EA-IV participants (median age 68.7 years, 82.3% male) were examined. Comparing EA-IV and EA-V, no relevant differences in risk factor prevalence and lifestyle changes were observed with the exception of lower LDL cholesterol levels in EA-V. Prevalence of unrecognized diabetes was significantly lower in EA-V as compared to EA-IV (11.8% vs. 19.6%) while the proportion of prediabetes was similarly high in the remaining population (62.1% vs. 61.0%). CONCLUSION: Between 2012 and 2017, a modest decrease in LDL cholesterol levels was observed, while no differences in blood pressure control and body weight were apparent in chronic CHD patients in Germany. Although the prevalence of unrecognized diabetes decreased in the later study period, the proportion of normoglycemic patients was low. As pharmacotherapy appeared fairly well implemented, stronger efforts towards lifestyle interventions, mental health programs and cardiac rehabilitation might help to improve risk factor profiles in chronic CHD patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00392-022-02093-0. |
format | Online Article Text |
id | pubmed-9898414 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-98984142023-02-05 Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys Ungethüm, K. Wiedmann, S. Wagner, M. Leyh, R. Ertl, G. Frantz, S. Geisler, T. Karmann, W. Prondzinsky, R. Herdeg, C. Noutsias, M. Ludwig, T. Käs, J. Klocke, B. Krapp, J. Wood, D. Kotseva, K. Störk, S. Heuschmann, P. U. Clin Res Cardiol Original Paper BACKGROUND: Patients with coronary heart disease (CHD) with and without diabetes mellitus have an increased risk of recurrent events requiring multifactorial secondary prevention of cardiovascular risk factors. We compared prevalences of cardiovascular risk factors and its determinants including lifestyle, pharmacotherapy and diabetes mellitus among patients with chronic CHD examined within the fourth and fifth EUROASPIRE surveys (EA-IV, 2012–13; and EA-V, 2016–17) in Germany. METHODS: The EA initiative iteratively conducts European-wide multicenter surveys investigating the quality of secondary prevention in chronic CHD patients aged 18 to 79 years. The data collection in Germany was performed during a comprehensive baseline visit at study centers in Würzburg (EA-IV, EA-V), Halle (EA-V), and Tübingen (EA-V). RESULTS: 384 EA-V participants (median age 69.0 years, 81.3% male) and 536 EA-IV participants (median age 68.7 years, 82.3% male) were examined. Comparing EA-IV and EA-V, no relevant differences in risk factor prevalence and lifestyle changes were observed with the exception of lower LDL cholesterol levels in EA-V. Prevalence of unrecognized diabetes was significantly lower in EA-V as compared to EA-IV (11.8% vs. 19.6%) while the proportion of prediabetes was similarly high in the remaining population (62.1% vs. 61.0%). CONCLUSION: Between 2012 and 2017, a modest decrease in LDL cholesterol levels was observed, while no differences in blood pressure control and body weight were apparent in chronic CHD patients in Germany. Although the prevalence of unrecognized diabetes decreased in the later study period, the proportion of normoglycemic patients was low. As pharmacotherapy appeared fairly well implemented, stronger efforts towards lifestyle interventions, mental health programs and cardiac rehabilitation might help to improve risk factor profiles in chronic CHD patients. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00392-022-02093-0. Springer Berlin Heidelberg 2022-09-27 2023 /pmc/articles/PMC9898414/ /pubmed/36166067 http://dx.doi.org/10.1007/s00392-022-02093-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Original Paper Ungethüm, K. Wiedmann, S. Wagner, M. Leyh, R. Ertl, G. Frantz, S. Geisler, T. Karmann, W. Prondzinsky, R. Herdeg, C. Noutsias, M. Ludwig, T. Käs, J. Klocke, B. Krapp, J. Wood, D. Kotseva, K. Störk, S. Heuschmann, P. U. Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title | Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title_full | Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title_fullStr | Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title_full_unstemmed | Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title_short | Secondary prevention in diabetic and nondiabetic coronary heart disease patients: Insights from the German subset of the hospital arm of the EUROASPIRE IV and V surveys |
title_sort | secondary prevention in diabetic and nondiabetic coronary heart disease patients: insights from the german subset of the hospital arm of the euroaspire iv and v surveys |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898414/ https://www.ncbi.nlm.nih.gov/pubmed/36166067 http://dx.doi.org/10.1007/s00392-022-02093-0 |
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