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Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway

The uvula flapping is one of the most distinctive features of snoring and is critical in affecting airway aerodynamics and vibrations. This study aimed to elucidate the mechanism of pharyngeal vibration and pressure fluctuation due to uvula flapping employing fluid–structure interaction simulations....

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Autores principales: Chen, Yicheng, Feng, Xin, Shi, Xie-Qi, Cai, Weihua, Li, Biao, Zhao, Yijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898500/
https://www.ncbi.nlm.nih.gov/pubmed/36737491
http://dx.doi.org/10.1038/s41598-023-28994-2
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author Chen, Yicheng
Feng, Xin
Shi, Xie-Qi
Cai, Weihua
Li, Biao
Zhao, Yijun
author_facet Chen, Yicheng
Feng, Xin
Shi, Xie-Qi
Cai, Weihua
Li, Biao
Zhao, Yijun
author_sort Chen, Yicheng
collection PubMed
description The uvula flapping is one of the most distinctive features of snoring and is critical in affecting airway aerodynamics and vibrations. This study aimed to elucidate the mechanism of pharyngeal vibration and pressure fluctuation due to uvula flapping employing fluid–structure interaction simulations. The followings are the methodology part: we constructed an anatomically accurate pediatric pharynx model and put attention on the oropharynx region where the greatest level of upper airway compliance was reported to occur. The uvula was assumed to be a rigid body with specific flapping frequencies to guarantee proper boundary conditions with as little complexity as possible. The airway tissue was considered to have a uniform thickness. It was found that the flapping frequency had a more significant effect on the airway vibration than the flapping amplitude, as the flapping uvula influenced the pharyngeal aerodynamics by altering the jet flow from the mouth. Breathing only through the mouth could amplify the effect of flapping uvula on aerodynamic changes and result in more significant oropharynx vibration.
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spelling pubmed-98985002023-02-05 Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway Chen, Yicheng Feng, Xin Shi, Xie-Qi Cai, Weihua Li, Biao Zhao, Yijun Sci Rep Article The uvula flapping is one of the most distinctive features of snoring and is critical in affecting airway aerodynamics and vibrations. This study aimed to elucidate the mechanism of pharyngeal vibration and pressure fluctuation due to uvula flapping employing fluid–structure interaction simulations. The followings are the methodology part: we constructed an anatomically accurate pediatric pharynx model and put attention on the oropharynx region where the greatest level of upper airway compliance was reported to occur. The uvula was assumed to be a rigid body with specific flapping frequencies to guarantee proper boundary conditions with as little complexity as possible. The airway tissue was considered to have a uniform thickness. It was found that the flapping frequency had a more significant effect on the airway vibration than the flapping amplitude, as the flapping uvula influenced the pharyngeal aerodynamics by altering the jet flow from the mouth. Breathing only through the mouth could amplify the effect of flapping uvula on aerodynamic changes and result in more significant oropharynx vibration. Nature Publishing Group UK 2023-02-03 /pmc/articles/PMC9898500/ /pubmed/36737491 http://dx.doi.org/10.1038/s41598-023-28994-2 Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Article
Chen, Yicheng
Feng, Xin
Shi, Xie-Qi
Cai, Weihua
Li, Biao
Zhao, Yijun
Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title_full Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title_fullStr Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title_full_unstemmed Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title_short Computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
title_sort computational fluid–structure interaction analysis of flapping uvula on aerodynamics and pharyngeal vibration in a pediatric airway
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898500/
https://www.ncbi.nlm.nih.gov/pubmed/36737491
http://dx.doi.org/10.1038/s41598-023-28994-2
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