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Confined environments induce polarized paraspeckle condensates

Cancer cells experience confinement as they navigate the tumour microenvironment during metastasis. Recent studies have revealed that the nucleus can function as a ‘ruler’ for measuring physical confinement via membrane tension, allowing for compression-sensitive changes in migration. Cell nuclei co...

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Detalles Bibliográficos
Autores principales: Todorovski, Vanja, McCluggage, Finn, Li, Yixuan, Meid, Annika, Spatz, Joachim P., Holle, Andrew W., Fox, Archa H., Choi, Yu Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898560/
https://www.ncbi.nlm.nih.gov/pubmed/36737664
http://dx.doi.org/10.1038/s42003-023-04528-4