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Confined environments induce polarized paraspeckle condensates
Cancer cells experience confinement as they navigate the tumour microenvironment during metastasis. Recent studies have revealed that the nucleus can function as a ‘ruler’ for measuring physical confinement via membrane tension, allowing for compression-sensitive changes in migration. Cell nuclei co...
Autores principales: | Todorovski, Vanja, McCluggage, Finn, Li, Yixuan, Meid, Annika, Spatz, Joachim P., Holle, Andrew W., Fox, Archa H., Choi, Yu Suk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898560/ https://www.ncbi.nlm.nih.gov/pubmed/36737664 http://dx.doi.org/10.1038/s42003-023-04528-4 |
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