QSAR modeling and molecular docking studies of 2-oxo-1, 2-dihydroquinoline-4- carboxylic acid derivatives as p-glycoprotein inhibitors for combating cancer multidrug resistance()

Multidrug resistance (MDR) proteins related to the ATP-binding cassette family are found in a very wide range of human tumors and result in therapeutic failure. The overexpression of efflux pumps such as ABCB1 is one of the mechanisms of MDR. This paper aims to develop a reliable quantitative struct...

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Detalles Bibliográficos
Autores principales: Lahyaoui, M., Diane, A., El-Idrissi, H., Saffaj, T., Rodi, Y. Kandri, Ihssane, B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898678/
https://www.ncbi.nlm.nih.gov/pubmed/36747956
http://dx.doi.org/10.1016/j.heliyon.2023.e13020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898678/
https://www.ncbi.nlm.nih.gov/pubmed/36747956
http://dx.doi.org/10.1016/j.heliyon.2023.e13020

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