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SARS-COV-2 spike protein promotes RPE cell senescence via the ROS/P53/P21 pathway

SARS-Cov-2 infection, which has caused the COVID-19 global pandemic, triggers cellular senescence. In this study, we investigate the role of the SARS-COV-2 spike protein (S-protein) in regulating the senescence of RPE cells. The results showed that administration or overexpression of S-protein in AR...

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Detalles Bibliográficos
Autores principales:	Zhang, Yuhang, Peng, Xuyan, Xue, Mengjiao, Liu, Jingjing, Shang, Guohui, Jiang, Mingjun, Chen, Dandan, Liu, Baixue, Wang, Yuxuan, Jia, Xiaolin, Xu, Jianqing, Zhang, Fengyan, Hu, Yanzhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898700/ https://www.ncbi.nlm.nih.gov/pubmed/36738354 http://dx.doi.org/10.1007/s10522-023-10019-0

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