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Intestinal fibrosis in aganglionic segment of Hirschsprung's disease revealed by single‐cell RNA sequencing

BACKGROUND: Hirschsprung's disease (HSCR) is a relatively common congenital disability. Accumulating extracellular matrix (ECM) prompts intestinal fibrosis remodelling in the aganglionic segments of HSCR. The contributions of various cellular subsets in the fibrogenesis of HSCR segments are poo...

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Detalles Bibliográficos
Autores principales: He, Shiwei, Wang, Junfeng, Huang, Yanlei, Kong, Fanyang, Yang, Ran, Zhan, Yong, Li, Zifeng, Ye, Chunjing, Meng, Lingdu, Ren, Yankang, Zhou, Ying, Chen, Gong, Shen, Zhen, Sun, Song, Zheng, Shan, Dong, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898741/
https://www.ncbi.nlm.nih.gov/pubmed/36738110
http://dx.doi.org/10.1002/ctm2.1193