Generation of glutamatergic/GABAergic neuronal co-cultures derived from human induced pluripotent stem cells for characterizing E/I balance in vitro

Obtaining mechanistic insights into the disruptions of neuronal excitation and inhibition (E/I) balance in brain disorders has remained challenging. Here, we present a protocol for in vitro characterization of E/I balance. Using human induced pluripotent stem cells, we describe the generation of glu...

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Detalles Bibliográficos
Autores principales: Wang, Shan, Hesen, Rick, Mossink, Britt, Nadif Kasri, Nael, Schubert, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898783/
https://www.ncbi.nlm.nih.gov/pubmed/36856768
http://dx.doi.org/10.1016/j.xpro.2022.101967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898783/
https://www.ncbi.nlm.nih.gov/pubmed/36856768
http://dx.doi.org/10.1016/j.xpro.2022.101967

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