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Generation of glutamatergic/GABAergic neuronal co-cultures derived from human induced pluripotent stem cells for characterizing E/I balance in vitro
Obtaining mechanistic insights into the disruptions of neuronal excitation and inhibition (E/I) balance in brain disorders has remained challenging. Here, we present a protocol for in vitro characterization of E/I balance. Using human induced pluripotent stem cells, we describe the generation of glu...
Autores principales: | Wang, Shan, Hesen, Rick, Mossink, Britt, Nadif Kasri, Nael, Schubert, Dirk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898783/ https://www.ncbi.nlm.nih.gov/pubmed/36856768 http://dx.doi.org/10.1016/j.xpro.2022.101967 |
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