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ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data

Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic f...

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Autores principales: Masson, Helen O., Borland, David, Reilly, Jason, Telleria, Adrian, Shrivastava, Shalki, Watson, Matt, Bustillos, Luthfi, Li, Zerong, Capps, Laura, Kellman, Benjamin P., King, Zachary A., Richelle, Anne, Lewis, Nathan E., Robasky, Kimberly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898792/
https://www.ncbi.nlm.nih.gov/pubmed/36853701
http://dx.doi.org/10.1016/j.xpro.2023.102069
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author Masson, Helen O.
Borland, David
Reilly, Jason
Telleria, Adrian
Shrivastava, Shalki
Watson, Matt
Bustillos, Luthfi
Li, Zerong
Capps, Laura
Kellman, Benjamin P.
King, Zachary A.
Richelle, Anne
Lewis, Nathan E.
Robasky, Kimberly
author_facet Masson, Helen O.
Borland, David
Reilly, Jason
Telleria, Adrian
Shrivastava, Shalki
Watson, Matt
Bustillos, Luthfi
Li, Zerong
Capps, Laura
Kellman, Benjamin P.
King, Zachary A.
Richelle, Anne
Lewis, Nathan E.
Robasky, Kimberly
author_sort Masson, Helen O.
collection PubMed
description Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. We explain how to set up a run using publicly available omics data and how to visualize the results. The ImmCellFie algorithm pushes beyond conventional statistical enrichment and incorporates complex biological mechanisms to quantify cell activity. For complete details on the use and execution of this protocol, please refer to Richelle et al. (2021).(1)
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spelling pubmed-98987922023-02-05 ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data Masson, Helen O. Borland, David Reilly, Jason Telleria, Adrian Shrivastava, Shalki Watson, Matt Bustillos, Luthfi Li, Zerong Capps, Laura Kellman, Benjamin P. King, Zachary A. Richelle, Anne Lewis, Nathan E. Robasky, Kimberly STAR Protoc Protocol Understanding cellular metabolism is important across biotechnology and biomedical research and has critical implications in a broad range of normal and pathological conditions. Here, we introduce the user-friendly web-based platform ImmCellFie, which allows the comprehensive analysis of metabolic functions inferred from transcriptomic or proteomic data. We explain how to set up a run using publicly available omics data and how to visualize the results. The ImmCellFie algorithm pushes beyond conventional statistical enrichment and incorporates complex biological mechanisms to quantify cell activity. For complete details on the use and execution of this protocol, please refer to Richelle et al. (2021).(1) Elsevier 2023-01-25 /pmc/articles/PMC9898792/ /pubmed/36853701 http://dx.doi.org/10.1016/j.xpro.2023.102069 Text en © 2023 The Author(s) https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Protocol
Masson, Helen O.
Borland, David
Reilly, Jason
Telleria, Adrian
Shrivastava, Shalki
Watson, Matt
Bustillos, Luthfi
Li, Zerong
Capps, Laura
Kellman, Benjamin P.
King, Zachary A.
Richelle, Anne
Lewis, Nathan E.
Robasky, Kimberly
ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title_full ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title_fullStr ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title_full_unstemmed ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title_short ImmCellFie: A user-friendly web-based platform to infer metabolic function from omics data
title_sort immcellfie: a user-friendly web-based platform to infer metabolic function from omics data
topic Protocol
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898792/
https://www.ncbi.nlm.nih.gov/pubmed/36853701
http://dx.doi.org/10.1016/j.xpro.2023.102069
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