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copa-1 mutants experience heightened endoplasmic reticulum stress sensitivity in a C. elegans COPA Syndrome model

COPA Syndrome is a rare, autosomal dominant autoimmune/autoinflammatory disease caused by mutations in COPA , which codes for the alpha subunit of the Coat Protein Complex I (COPI). COPI coated vesicles move proteins in retrograde from the Golgi Apparatus to the Endoplasmic Reticulum. At the cellula...

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Detalles Bibliográficos
Autores principales: Larkin, Kerry A., Zafra, Izabella, Golden, Andy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Caltech Library 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898814/
https://www.ncbi.nlm.nih.gov/pubmed/36748043
http://dx.doi.org/10.17912/micropub.biology.000696