Structure-function analysis of CYP719As involved in methylenedioxy bridge-formation in the biosynthesis of benzylisoquinoline alkaloids and its de novo production

Benzylisoquinoline alkaloids (BIAs) are a type of secondary metabolite with clinical application value. (S)-stylopine is a special BIA which contains methylenedioxy bridge structures. CYP719As could catalyze the methylenedioxy bridge-formation on the A or D rings of protoberberine alkaloids, while d...

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Detalles Bibliográficos
Autores principales: Liu, Xiuyu, Jiao, Xiang, Cheng, Yatian, Ma, Ying, Bu, Junling, Jin, Baolong, Li, Qishuang, Hu, Zhimin, Tang, Jinfu, Lai, Changjiangsheng, Wang, Jian, Cui, Guanghong, Chen, Yun, Guo, Juan, Huang, Luqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898898/
https://www.ncbi.nlm.nih.gov/pubmed/36737755
http://dx.doi.org/10.1186/s12934-023-02024-2

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