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Widespread amyloidogenicity potential of multiple myeloma patient-derived immunoglobulin light chains

BACKGROUND: In a range of human disorders such as multiple myeloma (MM), immunoglobulin light chains (IgLCs) can be produced at very high concentrations. This can lead to pathological aggregation and deposition of IgLCs in different tissues, which in turn leads to severe and potentially fatal organ...

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Detalles Bibliográficos
Autores principales:	Sternke-Hoffmann, Rebecca, Pauly, Thomas, Norrild, Rasmus K., Hansen, Jan, Tucholski, Florian, Høie, Magnus Haraldson, Marcatili, Paolo, Dupré, Mathieu, Duchateau, Magalie, Rey, Martial, Malosse, Christian, Metzger, Sabine, Boquoi, Amelie, Platten, Florian, Egelhaaf, Stefan U., Chamot-Rooke, Julia, Fenk, Roland, Nagel-Steger, Luitgard, Haas, Rainer, Buell, Alexander K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898917/ https://www.ncbi.nlm.nih.gov/pubmed/36737754 http://dx.doi.org/10.1186/s12915-022-01506-w

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