Spectrum and clinical features of gene mutations in Chinese pediatric acute lymphoblastic leukemia

PURPOSE: The 5-year survival rate of children with acute lymphoblastic leukemia (ALL) is 85–90%, with a 10–15% rate of treatment failure. Next-generation sequencing (NGS) identified recurrent mutated genes in ALL that might alter the diagnosis, classification, prognostic stratification, treatment, a...

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Detalles Bibliográficos
Autores principales: Shen, Diying, Liu, Lixia, Xu, Xiaojun, Song, Hua, Zhang, Jingying, Xu, Weiqun, Zhao, Fenying, Liang, Juan, Liao, Chan, Wang, Yan, Xia, Tian, Wang, Chengcheng, Lou, Feng, Cao, Shanbo, Qin, Jiayue, Tang, Yongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898934/
https://www.ncbi.nlm.nih.gov/pubmed/36739388
http://dx.doi.org/10.1186/s12887-023-03856-y

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