Genome-wide screening reveals the genetic basis of mammalian embryonic eye development

BACKGROUND: Microphthalmia, anophthalmia, and coloboma (MAC) spectrum disease encompasses a group of eye malformations which play a role in childhood visual impairment. Although the predominant cause of eye malformations is known to be heritable in nature, with 80% of cases displaying loss-of-functi...

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Detalles Bibliográficos
Autores principales: Chee, Justine M., Lanoue, Louise, Clary, Dave, Higgins, Kendall, Bower, Lynette, Flenniken, Ann, Guo, Ruolin, Adams, David J., Bosch, Fatima, Braun, Robert E., Brown, Steve D. M., Chin, H.-J. Genie, Dickinson, Mary E., Hsu, Chih-Wei, Dobbie, Michael, Gao, Xiang, Galande, Sanjeev, Grobler, Anne, Heaney, Jason D., Herault, Yann, de Angelis, Martin Hrabe, Mammano, Fabio, Nutter, Lauryl M. J., Parkinson, Helen, Qin, Chuan, Shiroishi, Toshi, Sedlacek, Radislav, Seong, J-K, Xu, Ying, Brooks, Brian, McKerlie, Colin, Lloyd, K. C. Kent, Westerberg, Henrik, Moshiri, Ala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9898963/
https://www.ncbi.nlm.nih.gov/pubmed/36737727
http://dx.doi.org/10.1186/s12915-022-01475-0

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