Cargando…

Inhibition of castration-resistant prostate cancer growth by genistein through suppression of AKR1C3

BACKGROUND: Prostate cancer is the second leading cause of cancer-related death among males in America. The patients’ survival time is significantly reduced after prostate cancer develops into castration-resistant prostate cancer (CRPC). It has been reported that AKR1C3 is involved in this progressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yu, Xiaoping, Yan, Jiali, Li, Yulu, Cheng, Jing, Zheng, Lujie, Fu, Tianyu, Zhu, Yanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Open Academia 2023
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899042/ https://www.ncbi.nlm.nih.gov/pubmed/36794010 http://dx.doi.org/10.29219/fnr.v67.9024

Ejemplares similares

siAKR1C3@PPA complex nucleic acid nanoparticles inhibit castration-resistant prostate cancer in vitro
por: Cui, Xiaoli, et al.
Publicado: (2022)

Genistein Suppresses Prostate Cancer Growth through Inhibition of Oncogenic MicroRNA-151
por: Chiyomaru, Takeshi, et al.
Publicado: (2012)

20(S)-Protopanaxadiol Inhibition of Progression and Growth of Castration-Resistant Prostate Cancer
por: Cao, Bo, et al.
Publicado: (2014)

AKR1C3 Inhibition Therapy in Castration-Resistant Prostate Cancer and Breast Cancer: Lessons from Responses to SN33638
por: Zhou, Wen, et al.
Publicado: (2014)

Suppression of lymphoma growth by the xenoestrogens bisphenol A and genistein
por: Yakimchuk, Konstantin, et al.
Publicado: (2018)

Estradiol suppresses tissue androgens and prostate cancer growth in castration resistant prostate cancer
por: Montgomery, Bruce, et al.
Publicado: (2010)

A Mansonone Derivative Coupled with Monoclonal Antibody 4D5-Modified Chitosan Inhibit AKR1C3 to Treat Castration-Resistant Prostate Cancer
por: Zhou, Meng, et al.
Publicado: (2020)

Menin inhibition suppresses castration-resistant prostate cancer and enhances chemosensitivity
por: Cherif, Chaïma, et al.
Publicado: (2021)

Genistein inhibits the contact-stimulated migration of prostate cancer cells
por: Miękus, Katarzyna, et al.
Publicado: (2007)

Establishing a Proteomics-Based Signature of AKR1C3-Related Genes for Predicting the Prognosis of Prostate Cancer
por: Cui, Xiaoli, et al.
Publicado: (2023)

AKR1C3 Converts Castrate and Post-Abiraterone DHEA-S into Testosterone to Stimulate Growth of Prostate Cancer Cells via 5-Androstene-3β,17β-Diol
por: Detlefsen, Andrea J., et al.
Publicado: (2023)

Plasma Exosomal AKR1C3 mRNA Expression Is a Predictive and Prognostic Biomarker in Patients with Metastatic Castration-Resistant Prostate Cancer
por: Zhu, Sha, et al.
Publicado: (2022)

Development of Potent and Selective Indomethacin Analogues for the Inhibition of AKR1C3 (Type 5 17β-Hydroxysteroid Dehydrogenase/Prostaglandin F Synthase) in Castrate-Resistant Prostate Cancer
por: Liedtke, Andy J., et al.
Publicado: (2013)

Genistein Inhibits Prostate Cancer Cell Growth by Targeting miR-34a and Oncogenic HOTAIR
por: Chiyomaru, Takeshi, et al.
Publicado: (2013)

Genistein suppresses FLT4 and inhibits human colorectal cancer metastasis
por: Xiao, Xiao, et al.
Publicado: (2014)

The Activity of SN33638, an Inhibitor of AKR1C3, on Testosterone and 17β-Estradiol Production and Function in Castration-Resistant Prostate Cancer and ER-Positive Breast Cancer
por: Yin, Yarong Diana, et al.
Publicado: (2014)

BET inhibitors potentiate melanoma ferroptosis and immunotherapy through AKR1C2 inhibition
por: Meng, Yu, et al.
Publicado: (2023)

Raloxifene Suppresses Tumor Growth and Metastasis in an Orthotopic Model of Castration-Resistant Prostate Cancer
por: Palmer, Hannah, et al.
Publicado: (2022)

Hydrazinobenzoylcurcumin inhibits androgen receptor activity and growth of castration-resistant prostate cancer in mice
por: Wu, Min, et al.
Publicado: (2015)

Non-digestible stachyose promotes bioavailability of genistein through inhibiting intestinal degradation and first-pass metabolism of genistein in mice
por: Lu, Yalong, et al.
Publicado: (2017)

AKR7A3 modulates the metastasis of pancreatic ductal adenocarcinoma through regulating PHGDH‐suppressed autophagy
por: Hua, Lei, et al.
Publicado: (2023)

Genistein chemoprevention of prostate cancer in TRAMP mice
por: Wang, Jun, et al.
Publicado: (2007)

Genistein suppresses the proliferation of telomerase‐negative cells
por: Lin, Chuan‐Chuan, et al.
Publicado: (2016)

Enzymes of the AKR1B and AKR1C Subfamilies and Uterine Diseases
por: Rižner, Tea Lanišnik
Publicado: (2012)

HDAC Inhibition Impedes Epithelial-Mesenchymal Plasticity and Suppresses Metastatic, Castration-Resistant Prostate Cancer
por: Ruscetti, Marcus, et al.
Publicado: (2015)

Knockdown of AKR1C3 Promoted Sorafenib Sensitivity Through Inhibiting the Phosphorylation of AKT in Hepatocellular Carcinoma
por: Zheng, Jia, et al.
Publicado: (2022)

Plasma genistein and risk of prostate cancer in Chinese population
por: Wu, Yishuo, et al.
Publicado: (2015)

Genistein inhibits estradiol- and environmental endocrine disruptor-induced growth effects on neuroblastoma cells in vitro
por: ZHENG, JICUI, et al.
Publicado: (2013)

Avasimibe inhibits tumor growth by targeting FoxM1-AKR1C1 in osteosarcoma
por: Wang, Liang, et al.
Publicado: (2019)

Ruthenium complexes show potent inhibition of AKR1C1, AKR1C2, and AKR1C3 enzymes and anti-proliferative action against chemoresistant ovarian cancer cell line
por: Kljun, Jakob, et al.
Publicado: (2022)

SIRNA-Directed In Vivo Silencing of Androgen Receptor Inhibits the Growth of Castration-Resistant Prostate Carcinomas
por: Compagno, Daniel, et al.
Publicado: (2007)

Cabozantinib Inhibits Growth of Androgen-Sensitive and Castration-Resistant Prostate Cancer and Affects Bone Remodeling
por: Nguyen, Holly M., et al.
Publicado: (2013)

Genistein Combined Polysaccharide (GCP) Can Inhibit Intracrine Androgen Synthesis in Prostate Cancer Cells
por: Batra, Neelu, et al.
Publicado: (2020)

Castration for Prostatic Hypertrophy
Publicado: (1899)

Genistein Suppresses LPS-Induced Inflammatory Response through Inhibiting NF-κB following AMP Kinase Activation in RAW 264.7 Macrophages
por: Ji, Guiyuan, et al.
Publicado: (2012)

Dietary intake of genistein suppresses hepatocellular carcinoma through AMPK-mediated apoptosis and anti-inflammation
por: Lee, Sang R., et al.
Publicado: (2019)

Patchouli alcohol suppresses castration-resistant prostate cancer progression by inhibiting NF-κB signal pathways
por: Cai, Jian, et al.
Publicado: (2022)

Exploiting the tumor-suppressive activity of the androgen receptor by CDK4/6 inhibition in castration-resistant prostate cancer
por: Han, Wanting, et al.
Publicado: (2022)

Inhibition of cancer cell invasion and metastasis by genistein
por: Pavese, Janet M., et al.
Publicado: (2010)

Genistein suppresses retinoblastoma cell viability and growth and induces apoptosis by upregulating miR-145 and inhibiting its target ABCE1
por: Wei, Dong, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_00n37r9m6ie0o3h19bchu49c32