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Streptococcus pyogenes vaccine candidates do not induce autoimmune responses in a rheumatic heart disease model

We have developed a candidate vaccine to protect against multiple strains of Streptococcus pyogenes infections. The candidate vaccine contains two synthetic peptides derived from S. pyogenes proteins: the M-protein epitope, p*17 and the IL-8 degrading S. pyogenes Cell-Envelope Proteinase (SpyCEP) ep...

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Detalles Bibliográficos
Autores principales:	Reynolds, Simone, Rafeek, Rukshan Ahamed Mohamed, Hamlin, Adam, Lepletier, Ailin, Pandey, Manisha, Ketheesan, Natkunam, Good, Michael F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899064/ https://www.ncbi.nlm.nih.gov/pubmed/36739443 http://dx.doi.org/10.1038/s41541-023-00604-2

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