Cargando…

Longitudinal DNA methylation analysis of adult-type IDH-mutant gliomas

Diffuse gliomas are the most prevalent malignant primary brain tumors in adults and remain incurable despite standard therapy. Tumor recurrence is currently inevitable, which contributes to a persistent high morbidity and mortality in these patients. In this study, we examined the genome-wide DNA me...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ferreyra Vega, Sandra, Olsson Bontell, Thomas, Kling, Teresia, Jakola, Asgeir Store, Carén, Helena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899392/ https://www.ncbi.nlm.nih.gov/pubmed/36739454 http://dx.doi.org/10.1186/s40478-023-01520-1

Ejemplares similares

Spatial heterogeneity in DNA methylation and chromosomal alterations in diffuse gliomas and meningiomas
por: Ferreyra Vega, Sandra, et al.
Publicado: (2022)

Intratumor DNA methylation heterogeneity in glioblastoma: implications for DNA methylation-based classification
por: Wenger, Anna, et al.
Publicado: (2019)

DNA methylation profiling for molecular classification of adult diffuse lower-grade gliomas
por: Ferreyra Vega, Sandra, et al.
Publicado: (2021)

Stalled oligodendrocyte differentiation in IDH-mutant gliomas
por: Wei, Yanfei, et al.
Publicado: (2023)

The clinical significance of the T2-FLAIR mismatch sign in grade II and III gliomas: a population-based study
por: Corell, Alba, et al.
Publicado: (2020)

The clinical value of proneural, classical and mesenchymal protein signatures in WHO 2021 adult-type diffuse lower-grade gliomas
por: Dénes, Anna, et al.
Publicado: (2023)

WHO Grade Loses Its Prognostic Value in Molecularly Defined Diffuse Lower-Grade Gliomas
por: Carstam, Louise, et al.
Publicado: (2022)

DNA methylation alterations across time and space in paediatric brain tumours
por: Wenger, Anna, et al.
Publicado: (2022)

Seizures in patients with IDH-mutated lower grade gliomas
por: Carstam, Louise, et al.
Publicado: (2022)

Stemness and clinical features in relation to the subventricular zone in diffuse lower-grade glioma: an exploratory study
por: Corell, Alba, et al.
Publicado: (2022)

Changes in clinical management of diffuse IDH-mutated lower-grade gliomas: patterns of care in a 15-year period
por: Svenjeby, Caroline, et al.
Publicado: (2022)

Preoperative Patient-Reported Outcomes in Suspected Low-Grade Glioma: Markers of Disease Severity and Correlations with Molecular Subtypes
por: Buvarp, Dongni, et al.
Publicado: (2021)

Is intracranial volume a risk factor for IDH-mutant low-grade glioma? A case–control study
por: Sagberg, Lisa Millgård, et al.
Publicado: (2022)

Accumulation of DNA methylation alterations in paediatric glioma stem cells following fractionated dose irradiation
por: Danielsson, Anna, et al.
Publicado: (2020)

DNA methylation profiling improves routine diagnosis of paediatric central nervous system tumours: A prospective population‐based study
por: Schepke, Elizabeth, et al.
Publicado: (2022)

DNA methylation-based age estimation in pediatric healthy tissues and brain tumors
por: Kling, Teresia, et al.
Publicado: (2020)

Moving from clinician-defined to patient-reported outcome measures for survivors of high-grade glioma
por: Rosenlund, Lena, et al.
Publicado: (2019)

Perioperative fatigue in patients with diffuse glioma
por: Schei, Stine, et al.
Publicado: (2020)

Methylation and transcription patterns are distinct in IDH mutant gliomas compared to other IDH mutant cancers
por: Unruh, Dusten, et al.
Publicado: (2019)

Is there a response shift in generic health-related quality of life 6 months after glioma surgery?
por: Jakola, Asgeir Store, et al.
Publicado: (2016)

Therapies for IDH-Mutant Gliomas
por: Alshiekh Nasany, Ruham, et al.
Publicado: (2023)

CRISPR-Cas9 knockout screen identifies novel treatment targets in childhood high-grade glioma
por: Wenger, Anna, et al.
Publicado: (2023)

A novel federated deep learning scheme for glioma and its subtype classification
por: Ali, Muhaddisa Barat, et al.
Publicado: (2023)

Validation of the MethylationEPIC BeadChip for fresh-frozen and formalin-fixed paraffin-embedded tumours
por: Kling, Teresia, et al.
Publicado: (2017)

Malignant Progression of an IDH Mutant Brainstem Glioma in Adult
por: SANO, Kenshi, et al.
Publicado: (2021)

Postoperative risk of IDH-mutant glioma–associated seizures and their potential management with IDH-mutant inhibitors
por: Drumm, Michael R., et al.
Publicado: (2023)

Neurosurgical patterns of care for diffuse low-grade gliomas in Sweden between 2005 and 2015
por: Carstam, Louise, et al.
Publicado: (2019)

Retrospective examination of pseudoprogression in IDH mutant gliomas
por: Wetzel, Ethan A, et al.
Publicado: (2023)

Updates on the WHO diagnosis of IDH-mutant glioma
por: Reuss, David.E.
Publicado: (2023)

Cell line-based xenograft mouse model of paediatric glioma stem cells mirrors the clinical course of the patient
por: Larsson, Susanna, et al.
Publicado: (2018)

Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis
por: Lee, Kwanghoon, et al.
Publicado: (2023)

Prediction of glioma-subtypes: comparison of performance on a DL classifier using bounding box areas versus annotated tumors
por: Ali, Muhaddisa Barat, et al.
Publicado: (2022)

DDRE-12. HETEROGENOUS RESPONSE OF IDH-MUTANT AND IDH-WT GLIOMA TO NAMPT INHIBITION
por: Rahman, Masum, et al.
Publicado: (2021)

Insulator dysfunction and oncogene activation in IDH mutant gliomas
por: Flavahan, William A., et al.
Publicado: (2015)

Metabolic Reprogramming in Mutant IDH1 Glioma Cells
por: Izquierdo-Garcia, Jose L., et al.
Publicado: (2015)

Mutant IDH1 Promotes Glioma Formation In Vivo
por: Philip, Beatrice, et al.
Publicado: (2018)

Epigenetic Reprogramming for Targeting IDH-Mutant Malignant Gliomas
por: Park, Jong-Whi, et al.
Publicado: (2019)

Proteome-based insights for IDH-mutant glioma classification
por: Leu, Severina, et al.
Publicado: (2023)

Mutant IDH in Gliomas: Role in Cancer and Treatment Options
por: Solomou, Georgios, et al.
Publicado: (2023)

Socioeconomic factors affect treatment delivery for patients with low grade glioma: a Swedish population-based study
por: Carstam, Louise, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_d3igmkl7j0q02a1rukncr10r7g