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Intestinal epithelium-specific Fut2 deficiency promotes colorectal cancer through down-regulating fucosylation of MCAM

BACKGROUND: Our previous study showed that fucosyltransferase 2 (Fut2) deficiency is closely related to colitis. Colitis increases the risk for the development of colorectal cancer (CRC). This study aimed to investigate the effect and underlying mechanism of action of Fut2 in CRC. METHODS: Intestina...

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Detalles Bibliográficos
Autores principales:	Wang, Weijun, Tang, Xuelian, Duan, Caihan, Tian, Shuxin, Han, Chaoqun, Qian, Wei, Jiang, Xin, Hou, Xiaohua, Lin, Rong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899399/ https://www.ncbi.nlm.nih.gov/pubmed/36739428 http://dx.doi.org/10.1186/s12967-023-03906-0

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