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SUMOylation of TUFT1 is essential for gastric cancer progression through AKT/mTOR signaling pathway activation

Tuftelin (TUFT1) is highly expressed in various tumor types and promotes tumor growth and metastasis by activating AKT and other core signaling pathways. However, the effects of post‐translational modifications of TUFT1 on its oncogenic function remain unexplored. In this study, we found that TUFT1...

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Detalles Bibliográficos
Autores principales: Wang, Tianning, Min, Lingyuan, Gao, Yan, Zhao, Mengmeng, Feng, Shaojie, Wang, Huiyun, Wang, Yunshan, Zheng, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899612/
https://www.ncbi.nlm.nih.gov/pubmed/36380570
http://dx.doi.org/10.1111/cas.15618

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