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Yes‐associated protein 1 mediates initial cell survival during lorlatinib treatment through AKT signaling in ROS1‐rearranged lung cancer
Tyrosine kinase inhibitors (TKIs) that target the ROS proto‐oncogene 1, receptor tyrosine kinase (ROS1) gene have shown dramatic therapeutic effects in patients with ROS1‐rearranged non‐small‐cell lung cancer (NSCLC). Nevertheless, advanced ROS1‐rearranged NSCLC is rarely cured as a portion of the t...
Autores principales: | Yamazoe, Masatoshi, Ozasa, Hiroaki, Tsuji, Takahiro, Funazo, Tomoko, Yoshida, Hiroshi, Hashimoto, Kentaro, Hosoya, Kazutaka, Ogimoto, Tatsuya, Ajimizu, Hitomi, Yoshida, Hironori, Itotani, Ryo, Sakamori, Yuichi, Kuninaga, Kiyomitsu, Aoki, Wataru, Hirai, Toyohiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899615/ https://www.ncbi.nlm.nih.gov/pubmed/36285485 http://dx.doi.org/10.1111/cas.15622 |
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