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Metformin and simvastatin synergistically suppress endothelin 1‐induced hypoxia and angiogenesis in multiple cancer types

Multiple cancers have been reported to be associated with angiogenesis and are sensitive to anti‐angiogenic therapies. Vascular normalization, by restoring proper tumor perfusion and oxygenation, could limit tumor cell invasiveness and improve the effectiveness of anticancer treatments. However, the...

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Detalles Bibliográficos
Autores principales: Liu, Jie, Wang, Huxia, Zhang, Miao, Li, Yazhao, Wang, Ruiqi, Chen, He, Wang, Bo, Gao, Xiaoqian, Song, Shaoran, Wang, Yaochun, Ren, Yu, Li, Juan, Liu, Peijun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899631/
https://www.ncbi.nlm.nih.gov/pubmed/36156330
http://dx.doi.org/10.1111/cas.15602