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Sialylated IgG in epithelial cancers inhibits antitumor function of T cells via Siglec‐7

Although effective, immune checkpoint blockade induces response in only a subset of cancer patients. There is an urgent need to discover new immune checkpoint targets. Recently, it was found that a class of sialic acid–binding immunoglobulin‐like lectins (Siglecs) expressed on the surface of T cells...

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Detalles Bibliográficos
Autores principales: Fan, Tianrui, Liao, Qinyuan, Zhao, Yang, Dai, Hui, Song, Shiyu, He, Tianhui, Wang, Zihan, Huang, Jing, Zeng, Zexian, Guo, Hongyan, Zhang, Haizeng, Qiu, Xiaoyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899632/
https://www.ncbi.nlm.nih.gov/pubmed/36310398
http://dx.doi.org/10.1111/cas.15631