Boron nitride nanocage as drug delivery systems for chloroquine, as an effective drug for treatment of coronavirus disease: A DFT study

Research has shown that chloroquine (CQ) can effectively help control COVID-19 infection. B(24)N(24) nanocage is a drug delivery system. Thus, through density functional theory, the present study analyzed pristine nanocage-CQ interaction and CQ interaction with Si- and Al -doped nanocage. The findin...

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Detalles Bibliográficos
Autores principales: Alharthy, Khalid M., Fadhil Alsaffar, Marwa, Althurwi, Hassan N., Albaqami, Faisal F., Reidh Abass, Russul, Majid Alawi, Aisha, Salah Jalal, Sarah, Tabassum, Shazia, Zhang, Hao, Peng, Wang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2023
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899703/
https://www.ncbi.nlm.nih.gov/pubmed/36777967
http://dx.doi.org/10.1016/j.inoche.2023.110482
Descripción
Sumario:Research has shown that chloroquine (CQ) can effectively help control COVID-19 infection. B(24)N(24) nanocage is a drug delivery system. Thus, through density functional theory, the present study analyzed pristine nanocage-CQ interaction and CQ interaction with Si- and Al -doped nanocage. The findings revealed that nanocage doping, particularly with Si and Al, yields more satisfactory drug delivery for CQ due to their greater electronic and energetic characteristics with CQ.

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