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Large animal models in the study of gynecological diseases
Gynecological diseases are a series of diseases caused by abnormalities in the female reproductive organs or breast, which endanger women’s fertility and even their lives. Therefore, it is important to investigate the mechanism of occurrence and treatment of gynecological diseases. Animal models are...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899856/ https://www.ncbi.nlm.nih.gov/pubmed/36755972 http://dx.doi.org/10.3389/fcell.2023.1110551 |
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author | Cui, Minghua Liu, Yuehui Men, Xiaoping Li, Tao Liu, Da Deng, Yongzhi |
author_facet | Cui, Minghua Liu, Yuehui Men, Xiaoping Li, Tao Liu, Da Deng, Yongzhi |
author_sort | Cui, Minghua |
collection | PubMed |
description | Gynecological diseases are a series of diseases caused by abnormalities in the female reproductive organs or breast, which endanger women’s fertility and even their lives. Therefore, it is important to investigate the mechanism of occurrence and treatment of gynecological diseases. Animal models are the main objects for people to study the development of diseases and explore treatment options. Large animals, compared to small rodents, have reproductive organs with structural and physiological characteristics closer to those of humans, and are also better suited for long-term serial examinations for gynecological disease studies. This review gives examples of large animal models in gynecological diseases and provides a reference for the selection of animal models for gynecological diseases. |
format | Online Article Text |
id | pubmed-9899856 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-98998562023-02-07 Large animal models in the study of gynecological diseases Cui, Minghua Liu, Yuehui Men, Xiaoping Li, Tao Liu, Da Deng, Yongzhi Front Cell Dev Biol Cell and Developmental Biology Gynecological diseases are a series of diseases caused by abnormalities in the female reproductive organs or breast, which endanger women’s fertility and even their lives. Therefore, it is important to investigate the mechanism of occurrence and treatment of gynecological diseases. Animal models are the main objects for people to study the development of diseases and explore treatment options. Large animals, compared to small rodents, have reproductive organs with structural and physiological characteristics closer to those of humans, and are also better suited for long-term serial examinations for gynecological disease studies. This review gives examples of large animal models in gynecological diseases and provides a reference for the selection of animal models for gynecological diseases. Frontiers Media S.A. 2023-01-23 /pmc/articles/PMC9899856/ /pubmed/36755972 http://dx.doi.org/10.3389/fcell.2023.1110551 Text en Copyright © 2023 Cui, Liu, Men, Li, Liu and Deng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cell and Developmental Biology Cui, Minghua Liu, Yuehui Men, Xiaoping Li, Tao Liu, Da Deng, Yongzhi Large animal models in the study of gynecological diseases |
title | Large animal models in the study of gynecological diseases |
title_full | Large animal models in the study of gynecological diseases |
title_fullStr | Large animal models in the study of gynecological diseases |
title_full_unstemmed | Large animal models in the study of gynecological diseases |
title_short | Large animal models in the study of gynecological diseases |
title_sort | large animal models in the study of gynecological diseases |
topic | Cell and Developmental Biology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899856/ https://www.ncbi.nlm.nih.gov/pubmed/36755972 http://dx.doi.org/10.3389/fcell.2023.1110551 |
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