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Application of a new approach methodology (NAM)-based strategy for genotoxicity assessment of data-poor compounds

The conventional battery for genotoxicity testing is not well suited to assessing the large number of chemicals needing evaluation. Traditional in vitro tests lack throughput, provide little mechanistic information, and have poor specificity in predicting in vivo genotoxicity. New Approach Methodolo...

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Detalles Bibliográficos
Autores principales:	Fortin, Anne-Marie V., Long, Alexandra S., Williams, Andrew, Meier, Matthew J., Cox, Julie, Pinsonnault, Claire, Yauk, Carole L., White, Paul A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Toxicology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899896/ https://www.ncbi.nlm.nih.gov/pubmed/36756349 http://dx.doi.org/10.3389/ftox.2023.1098432

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