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Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts

Percutaneous treatment of symptomatic hepatic cysts includes simple drainage and drainage with sclerosing agents. We compared the efficacy of simple drainage with that of drainage with minocycline infusion for treating symptomatic hepatic cysts. We retrospectively evaluated 11 patients who underwent...

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Autores principales: Kinoshita, Satoshi, Nishizawa, Toshihiro, Tojo, Masaya, Hirai, Yuichiro, Nakazato, Yoshihiro, Miyanaga, Ryoichi, Fujimoto, Ai, Inoue, Kazuaki, Ebinuma, Hirotoshi, Suzuki, Hidekazu, Kikuchi, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: the Society for Free Radical Research Japan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899919/
https://www.ncbi.nlm.nih.gov/pubmed/36777076
http://dx.doi.org/10.3164/jcbn.22-89
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author Kinoshita, Satoshi
Nishizawa, Toshihiro
Tojo, Masaya
Hirai, Yuichiro
Nakazato, Yoshihiro
Miyanaga, Ryoichi
Fujimoto, Ai
Inoue, Kazuaki
Ebinuma, Hirotoshi
Suzuki, Hidekazu
Kikuchi, Masahiro
author_facet Kinoshita, Satoshi
Nishizawa, Toshihiro
Tojo, Masaya
Hirai, Yuichiro
Nakazato, Yoshihiro
Miyanaga, Ryoichi
Fujimoto, Ai
Inoue, Kazuaki
Ebinuma, Hirotoshi
Suzuki, Hidekazu
Kikuchi, Masahiro
author_sort Kinoshita, Satoshi
collection PubMed
description Percutaneous treatment of symptomatic hepatic cysts includes simple drainage and drainage with sclerosing agents. We compared the efficacy of simple drainage with that of drainage with minocycline infusion for treating symptomatic hepatic cysts. We retrospectively evaluated 11 patients who underwent percutaneous drainage of symptomatic hepatic cysts. In seven cases, minocycline infusion was added at the discretion of the clinician. Cyst volume was evaluated before drainage, immediately after drainage, and after long-term follow-up. Cyst volume was calculated before treatment by multiplying the orthogonal diameters using the ellipsoid formula. Relapse was defined as the regrowth of the cyst with symptoms. Cyst volume immediately after drainage and after long-term follow-up was significantly less than that before treatment for the drainage with minocycline infusion group (p<0.05) but not for the simple drainage group. The relapse rates were 25% (1/4) for the simple drainage group and 0% for the drainage with minocycline infusion group. Drainage with minocycline infusion could be a promising option for treating symptomatic hepatic cysts, although simple drainage was not reliable.
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spelling pubmed-98999192023-02-11 Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts Kinoshita, Satoshi Nishizawa, Toshihiro Tojo, Masaya Hirai, Yuichiro Nakazato, Yoshihiro Miyanaga, Ryoichi Fujimoto, Ai Inoue, Kazuaki Ebinuma, Hirotoshi Suzuki, Hidekazu Kikuchi, Masahiro J Clin Biochem Nutr Original Article Percutaneous treatment of symptomatic hepatic cysts includes simple drainage and drainage with sclerosing agents. We compared the efficacy of simple drainage with that of drainage with minocycline infusion for treating symptomatic hepatic cysts. We retrospectively evaluated 11 patients who underwent percutaneous drainage of symptomatic hepatic cysts. In seven cases, minocycline infusion was added at the discretion of the clinician. Cyst volume was evaluated before drainage, immediately after drainage, and after long-term follow-up. Cyst volume was calculated before treatment by multiplying the orthogonal diameters using the ellipsoid formula. Relapse was defined as the regrowth of the cyst with symptoms. Cyst volume immediately after drainage and after long-term follow-up was significantly less than that before treatment for the drainage with minocycline infusion group (p<0.05) but not for the simple drainage group. The relapse rates were 25% (1/4) for the simple drainage group and 0% for the drainage with minocycline infusion group. Drainage with minocycline infusion could be a promising option for treating symptomatic hepatic cysts, although simple drainage was not reliable. the Society for Free Radical Research Japan 2023-01 2022-11-09 /pmc/articles/PMC9899919/ /pubmed/36777076 http://dx.doi.org/10.3164/jcbn.22-89 Text en Copyright © 2023 JCBN https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License (http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) ).
spellingShingle Original Article
Kinoshita, Satoshi
Nishizawa, Toshihiro
Tojo, Masaya
Hirai, Yuichiro
Nakazato, Yoshihiro
Miyanaga, Ryoichi
Fujimoto, Ai
Inoue, Kazuaki
Ebinuma, Hirotoshi
Suzuki, Hidekazu
Kikuchi, Masahiro
Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title_full Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title_fullStr Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title_full_unstemmed Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title_short Simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
title_sort simple drainage versus drainage with minocycline infusion for symptomatic hepatic cysts
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9899919/
https://www.ncbi.nlm.nih.gov/pubmed/36777076
http://dx.doi.org/10.3164/jcbn.22-89
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